Adrenal fatigue is really a dysfunction of your brain’s communication with your adrenals (HPA axis), not the adrenal gland itself. Chronic stressors can cause cortisol to remain high for a long time. Chronically high cortisol levels can tire your adrenal glands out — this is adrenal fatigue.
Low Immune Function
Chronic stress on the brain and adrenals can effect your immune system the same way it effects your adrenals. 80% of your immune system is within the gut and chronic stress caused by adrenal fatigue can lead to a lowered immune system.
When your brain is shot your adrenal glands are not getting the message. Causing cortisol levels to be off causing it to be high when it should be low, low when it should be high, consistently low, or consistently too high. All of which can take a toll on your adrenal glands causing dysregulation.
Fatigue & Depression
When your cortisol rhythm is off your ability to handle stress will be weakened. Your brain and adrenal glands are also not communicating properly you’re blood sugar and pressure fluctuations which will mess with your energy.
With your cortisol levels influx and causing a flight or fight response within the body your hormones will also be influx. This can lead to increases in weight gain or even extreme weight loss.
Blood Sugar Fluctuations
Dysfunctions of your cortisol rhythm can bring blood pressure and blood sugar dysregulation.
When the brain/gut axis is compromised it can put extra stress on the adrenals leading to brain inflammation. Since your brain does not have pain censors a symptom of that brain inflammation can be brain fog.